Aging Research in Yeast (Subcellular Biochemistry)

Aging Research in Yeast (Subcellular Biochemistry) by Michael Breitenbach (Editor), S. Michal Jazwinski (Editor), Peter Laun (Editor)



This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain). Most mechanisms of aging are studied in yeast. Among them, this book discusses: mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses; the role of autophagy and mitophagy; the relationship of apoptosis to aging processes; the role of asymmetric segregation of damage in replicative aging; the role of replication stress; and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined.

Review

From the reviews: “This book compiles some of the most exciting and promising research to date in the fields of anti-aging, longevity, and possibly even rejuvenation. The authors’ research examines the role of senescence in yeast and how it may relate to the chaotic autophagy of cancer cells. In sum, Aging Research will stir interest in both scientific and non-scientific arenas.” (The Electric Review, October, 2012)

From the Back Cover

This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain). Most mechanisms of aging are studied in yeast. Among them, this book discusses: mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses; the role of autophagy and mitophagy; the relationship of apoptosis to aging processes; the role of asymmetric segregation of damage in replicative aging; the role of replication stress; and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined.

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Book Detail 

• Hardcover: 377 pages
• Publisher: Springer; 2012 edition (November 18, 2011)
• Language: English
• ISBN-10: 9400725604
• ISBN-13: 978-9400725607
• Product Dimensions: 9.8 x 6.4 x 0.9 inches
• Shipping Weight: 1.5 pounds

Advances in Food Biochemistry

Advances in Food Biochemistry by Fatih Yildiz (Editor)

Understanding the biochemistry of food is basic to all other research and development in the fields of food science, technology, and nutrition, and the past decade has seen accelerated progress in these areas. Advances in Food Biochemistry provides a unified exploration of foods from a biochemical perspective. Featuring illustrations to elucidate molecular concepts throughout the text, this volume examines a range of issues on the food spectrum, including:

• water and its relation to food
• the glycobiology of food components
• enzymes
• plant, animal, and human hormones
• functional foods, herbs, and dietary supplements
• flavor compounds in foods
• organic acids
• interactions between the environment with food components
• biological and lipid oxidation in foods
• food safety
• nutrition and the genetic makeup of individual food components

Dr. Fatih Yildiz has published an extensive body of research and has worked on food and nutrition science projects with the FAO, UNIDO, UNICEF, and NATO. Recently he received the Ambassador for Turkey Award from the European Federation of Food Science and Technology. Dr. Yildiz and the contributors to this volume have brought together their decades of experience and expertise to provide a top-notch resource for food science and policy professionals and advanced students on the cutting edge of food research.

About the Author

Dr. Fatih Yildiz teaches and conducts research in the biochemistry, biotechnology, and food engineering departments at the Middle East Technical University, Ankara, Turkey. He has done research projects with FAO, UNIDO, UNICEF, and NATO as a project director and has published more than research and review papers in international and national journals as the major author.

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Book Details

• Hardcover: 521 pages
• Publisher: CRC Press; 1 edition (December 16, 2009)
• Language: English
• ISBN-10: 0849374995
• ISBN-13: 978-0849374999
• Product Dimensions: 7 x 1.3 x 10 inches
• Shipping Weight: 1.9 pounds

Biochemistry by Reginald H. Garrett

Succeed in the course with BIOCHEMISTRY. The authors' innovative conceptual and organizing "Essential Questions" framework guides you through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world. Offering a balanced and streamlined presentation, this edition has been updated throughout with new material and revised presentations. This book is integrated with OWL, a powerful online learning system for chemistry that will help you improve your grades and master course concepts. 

In Biochemistry, the questions often are more exhilarating than the answers. This Updated Third Edition continues the unique conceptual and organizing framework, "Essential Questions." Guiding students through the density of the material by the use of section head questions, supporting concept statements, and summaries, this focused approach is supported by unparalleled text/media integration through 

BiochemistryNow, providing students with a seamless learning system. Beautifully and consistently illustrated, this text gives science majors the most current presentation of biochemistry available. Written by a chemist and a biologist, the book presents biochemistry from balanced perspectives. 

This Updated Edition includes "Emerging Insights into Biochemistry" at the end of each chapter, which present students with the latest advances in biochemical research. The Updated Edition also is enhanced by the power of the online assessment-centered learning tool, BiochemistryNow. This powerful online learning companion helps students gauge their unique study needs and provides them with a Personalized Learning plan that enhances their problem-solving skills and conceptual understanding.

About the Author Reginald H. Garrett

Reginald H. Garrett was educated in the Baltimore city public schools and at the Johns Hopkins University, where he received his Ph.D. in biology in 1968. Since that time, he has conducted research and taught biochemistry courses at the University of Virginia, where he is currently Professor of Biology. He is the author of numerous papers and review articles on biochemical, genetic, and molecular biological aspects of inorganic nitrogen metabolism. His early research focused on the pathway of nitrate assimilation in filamentous fungi. His investigations contributed substantially to our understanding of the enzymology, genetics, and regulation of this major pathway of biological nitrogen acquisition. More recently, he has collaborated in systems approaches to the metabolic basis of nutrition-related diseases. His research has been supported by grants from the National Institutes of Health, the National Science Foundation, and private industry. A member of the American Society for Biochemistry and Molecular Biology, Garrett is a former Fulbright Scholar, was twice Visiting Scholar at the University of Cambridge, and was Invited Professor at the University of Toulouse, France.

Charles M. Grisham received his B.S. in chemistry from the Illinois Institute of Technology in 1969 and his Ph.D. in chemistry from the University of Minnesota in 1973. Following a postdoctoral appointment at the Institute for Cancer Research in Philadelphia, he became Professor of Chemistry at the University of Virginia, where he teaches biochemistry, introductory chemistry, and physical chemistry. He has authored numerous papers and review articles on active transport of sodium, potassium, and calcium in mammalian systems, on protein kinase C, and on the applications of NMR and EPR spectroscopy to the study of biological systems. His work has been supported by the National Institutes of Health, the National Science Foundation, the Muscular Dystrophy Association of America, the Research Corporation, the American Heart Association and the American Chemical Society. A member of the American Society for Biochemistry and Molecular Biology, Grisham held the Knapp Chair in Chemistry in 1999 at the University of San Diego; was Visiting Scientist at the Aarhus University Institute of Physiology, Aarhus, Denmark, for two years; and received a Research Career Development Award from the National Institutes of Health.

• Hardcover: 1280 pages
• Publisher: Brooks Cole; 5 edition (January 5, 2012)
• Language: English
• ISBN-10: 1133106293
• ISBN-13: 978-1133106296
• Product Dimensions: 9.1 x 1.7 x 10.9 inches
• Shipping Weight: 5.4 pounds